Easiest way is store values in an array, and just like Mission put, use the onChange and IDs to signify what information it should change to
Here's a small example, by principle. I'm not too adept in javascript, but this should give a general idea, it only displays an alertbox, but from that, you should be able to figure something:
Code:
<script type="text/javascript">
var arr = new Array("Item 1", "Item 2", "Item 3");
function popup() {
var x=document.getElementById("pulldown").value;
alert(arr[x]);
}
</script>
<form>
<select id="pulldown" onChange="popup()">
<option value="0">Alpha</option>
<option value="1">Beta</option>
<option value="2">Gamma</option>
</select>
</form>